And it feels pretty good! It actually runs really well on my 12 GB RAM, 27″ display, mid 2010, iMac. In 1080p with settings on high … But I think I might have a smal bug with some face texture display thingy.
Edit: 2011-11-27 — Seams like Bethesda has released a patch during the night. Looks much better now! :-D